Selected Publications
Greenwald AC*, Darnell NG*, Hoefflin R*, Simkin D, Mount CW, Gonzalez Castro LN, Harnik Y, Dumont S, Hirsch D, Nomura M, Talpir T, Kedmi M, Goliand I, Medici G, Laffy J, Li B, Mangena V, Keren-Shaul H, Weller M, Addadi Y, Neidert MC, Suvà ML#, Tirosh I# (2024) Integrative spatial analysis reveals a multi-layered organization of glioblastoma. Cell 187(10):2485-2501
Highlighted in Cancer Discovery “Reflections on Advances in Cancer Research in 2024.”
Gavish A, Tyler M, Greenwald AC, Hoefflin R, Simkin D, Tschernichovsky R, Galili Darnell N, Somech E, Barbolin C, Antman T, Kovarsky D, Barrett T, Gonzalez Castro LN, Halder D, Chanoch-Myers R, Laffy J, Mints M, Wider A, Tal R, Spitzer A, Hara T, Raitses-Gurevich M, Stossel C, Golan T, Tirosh A, Suvà ML, Puram SV, Tirosh I (2023) Hallmarks of transcriptional intratumour heterogeneity across a thousand tumours. Nature 618(7965):598-606.
Highlighted in Nature, Cancer Cell, and Nature Reviews Genetics.
Kinker GS*, Greenwald AC*, Tal R, Orlova Z, Cuoco MS, McFarland JM, Warren A, Rodman C, Roth JA, Bender SA, Kumar B, Rocco JW, Fernandes PACM, Mader CC, Keren-Shaul H, Plotnikov A, Barr H, Tsherniak A, Rozenblatt-Rosen O, Krizhanovsky V, Puram SV, Regev A, Tirosh I (2020) Pan-cancer single-cell RNA-seq identifies recurring programs of cellular heterogeneity. Nature Genetics 52(11):1208-1218.
Highlighted in Cancer Discovery.
Greenwald AC, Licht T, Kumar S, Oladipupo SS, Iyer S, Grunewald M, Keshet E (2019) VEGF expands erythropoiesis via hypoxia-independent induction of erythropoietin in noncanonical perivascular stromal cells. Journal of Experimental Medicine 216(1):215-230.
Other Publications
Spitzer A*, Johnson KC*, Nomura M*, Garofano L*, Nehar-Belaid D, Darnell NG, Greenwald AC, Bussema L, Oh YT, Varn FS, D'Angelo F, Gritsch S, Anderson KJ, Migliozzi S, Gonzalez Castro LN, Chowdhury T, Robine N, Reeves C, Park JB, Lipsa A, Hertel F, Golebiewska A, Niclou SP, Nusrat L, Kellet S, Das S, Moon HE, Paek SH, Bielle F, Laurenge A, Di Stefano AL, Mathon B, Picca A, Sanson M, Tanaka S, Saito N, Ashley DM, Keir ST, Ligon KL, Huse JT, Yung WKA, Lasorella A#, Iavarone A#, Verhaak RGW#, Tirosh I#, Suvà ML# (2025) Deciphering the longitudinal trajectories of glioblastoma ecosystems by integrative single-cell genomics. Nature Genetics 57(5):1168-1178.
Nomura M*, Spitzer A*, Johnson KC*, Garofano L*, Nehar-Belaid D, Galili Darnell N, Greenwald AC, Bussema L, Oh YT, Varn FS, D'Angelo F, Gritsch S, Anderson KJ, Migliozzi S, Gonzalez Castro LN, ChowdhFury T, Robine N, Reeves C, Park JB, Lipsa A, Hertel F, Golebiewska A, Niclou SP, Nusrat L, Kellet S, Das S, Moon HE, Paek SH, Bielle F, Laurenge A, Di Stefano AL, Mathon B, Picca A, Sanson M, Tanaka S, Saito N, Ashley DM, Keir ST, Ligon KL, Huse JT, Yung WKA, Lasorella A#, Verhaak RGW#, Iavarone A#, Suvà ML#, Tirosh I# (2025) The multilayered transcriptional architecture of glioblastoma ecosystems. Nature Genetics. 57(5):1155-1167.
Boxer E*, Feigin N*, Tschernichovsky R*, Darnell NG, Greenwald AC, Hoefflin R, Kovarsky D, Simkin D, Turgeman S, Zhang L, Tirosh I. Emerging clinical applications of single-cell RNA sequencing in oncology. (2025) Nature Reviews Clinical Oncology 22(5):315-326. (Review)
Wang T, Roach MJ, Harvey K, Morlanes JE, Kiedik B, Al-Eryani G, Greenwald A, Kalavros N, Dezem FS, Ma Y, Pita-Juarez YH, Wise K, Degletagne C, Elz A, Hadadianpour A, Johanneson J, Pakiam F, Ryu H, Newell EW, Tonon L, Kohlway A, Drennon T, Abousoud J, Stott R, Lund P, Durruthy J, Vallejo AF, Li W, Salomon R, Kaczorowski D, Warren J, Butler LM, O'Toole S, Plummer J, Vlachos IS, Lundeberg J, Swarbrick A, Martelotto LG (2024) snPATHO-seq, a versatile FFPE single-nucleus RNA sequencing method to unlock pathology archives. Communications Biology 7(1):1340.
Hara T*, Chanoch-Myers R*, Mathewson ND, Myskiw C, Atta L, Bussema L, Eichhorn SW, Greenwald AC, Kinker GS, Rodman C, Gonzalez Castro LN, Wakimoto H, Rozenblatt-Rosen O, Zhuang X, Fan J, Hunter T, Verma IM, Wucherpfennig KW, Regev A, Suvà ML#, Tirosh I# (2021) Interactions between cancer cells and immune cells drive transitions to mesenchymal-like states in glioblastoma. Cancer Cell 39(6):779-792.
Highlighted in Cancer Cell.
*=equal co-authors #=corresponding authors